RT Book, Section
A1 Magro, Cynthia M.
A1 Crowson, A. Neil
A1 Harrist, Terence J.
A2 Barnhill, Raymond L.
A2 Crowson, A. Neil
A2 Magro, Cynthia M.
A2 Piepkorn, Michael W.
A2 Kutzner, Heinz
A2 Desman, Garrett T.
SR Print(0)
ID 1178388888
T1 Intraepidermal Vesiculopustular Diseases
T2 Barnhill's Dermatopathology, 4e
YR 2020
FD 2020
PB McGraw Hill Education
PP New York, NY
SN 9780071828222
LK dermatology.mhmedical.com/content.aspx?aid=1178388888
RD 2024/04/19
AB A  wide  variety  of  disorders  may  produce  intraepidermal  vesicles  and  pustules.  Distinct  diseases  may  have  similar  or  even  identical  pathologic  features.  In  addition,  the  histopathologic  findings  in  each  disease  evolve  over  time.  Thus  the  algorithmic  approach  to  diagnosis  in  this  group  is,  of  necessity,  complex  but  facilitates  the  diagnosis  in  this  group  of  disorders  (Figs.  7-1,  7-2,  7-3,  Table  7-1),  and  especially  when  correlated  to  clinical  and  historical  data  often  proves  essential.  The  algorithm  narrows  the  differential  diagnosis  to  a  few  entities  or  a  specific  diagnosis  through  evaluation  of  the  blister-cleft  separation  plane,  the  principal  pathologic  process,  and  if  present,  the  inflammatory  cell  complement.  Immunofluorescent  and/or  serologic  studies  are  of  paramount  importance.