RT Book, Section A1 Tannous, Zeina A1 Avram, Mathew M. A1 Tsao, Sandy A1 Avram, Marc R. SR Print(0) ID 1175821581 T1 Ablative Laser Resurfacing T2 Color Atlas of Cosmetic Dermatology, 2e YR 2011 FD 2011 PB The McGraw-Hill Companies, Inc. PP New York, NY SN 9780071635035 LK dermatology.mhmedical.com/content.aspx?aid=1175821581 RD 2023/03/31 AB Utilizing the principles of selective photothermolysis, ablative removal of skin in a precisely controlled fashion with resultant minimal surrounding thermal damage is achieved. The depth of tissue penetration is dependent on selective absorption of water. Immediate tissue effects are dependent on the spot size and power utilized as well as the speed of treatment administration. The time of laser–tissue interaction is the critical factor for residual thermal damage. Epidermal obliteration and(or partial ablation or coagulation of the upper dermis is the endpoint. Re-epithelialization results from the migration of cells that arise from surrounding follicular adnexae. Normal compact collagen and elastic fibers replace the amorphous elastotic dermal components, and normal, well-organized epithelial cells replace the disorganized photodamaged epidermis. Collagen remodeling is noted both intraoperatively via thermal shrinkage and contraction and postoperatively within the remodeling phase of wound healing.