RT Book, Section A1 Tannous, Zeina A1 Avram, Mathew M. A1 Tsao, Sandy A1 Avram, Marc R. SR Print(0) ID 1175822440 T1 Melasma T2 Color Atlas of Cosmetic Dermatology, 2e YR 2011 FD 2011 PB The McGraw-Hill Companies, Inc. PP New York, NY SN 9780071635035 LK dermatology.mhmedical.com/content.aspx?aid=1175822440 RD 2024/04/19 AB Melasma is an acquired brown macular hyperpigmentation usually of the face. It is far more common in females than in males. It usually presents bilaterally and symmetrically on the face, but extensor forearms may also be involved. There are believed to be three histologic variants of melasma: epidermal, dermal, and mixed dermal and epidermal. Epidermal melasma responds best to therapy. All forms have a high rate of recurrence, making this a frustrating condition to treat. Sun exposure, pregnancy, and oral contraceptive pills are all associated with its presentation and recurrence (Fig. 25.1).