RT Book, Section A1 Tannous, Zeina A1 Avram, Mathew M. A1 Tsao, Sandy A1 Avram, Marc R. SR Print(0) ID 1175823466 T1 Squamous Cell Carcinoma T2 Color Atlas of Cosmetic Dermatology, 2e YR 2011 FD 2011 PB The McGraw-Hill Companies, Inc. PP New York, NY SN 9780071635035 LK dermatology.mhmedical.com/content.aspx?aid=1175823466 RD 2024/04/18 AB Squamous cell carcinoma (SCC) most commonly originates from keratinocytes in sun-damaged skin either de novo or from a preexisting actinic keratosis or SCC in situ (also known as Bowen’s disease), predominantly affecting the head, neck, and arms. It can also arise in nonsun-exposed skin most commonly from chronic leg ulcers and burn scars.