RT Book, Section
A1 Baumann, Leslie
SR Print(0)
ID 1174542010
T1 Overview of Melanin Production
T2 Cosmeceuticals and Cosmetic Ingredients
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071793988
LK dermatology.mhmedical.com/content.aspx?aid=1174542010
RD 2024/04/20
AB Melanin  production  occurs  inside  the  melanosomes  located  in  the  melanocytes.  The  process  of  melanin  synthesis  begins  with  the  hydroxylation  of  tyrosine  to  3,4-dihydroxyphenylalanine  (DOPA)  using  the  enzyme  tyrosinase  (Figure  33-1).1  Two  types  of  melanin  are  produced:  eumelanin  and  pheomelanin.  The  relative  amounts  of  these  two  forms  of  melanin  determine  hair  color  and  skin  tone.  Individuals  with  darker  skin  tones  have  mostly  eumelanin  and  a  lower  level  of  pheomelanin,  while  the  opposite  is  true  in  people  with  a  light  skin  color.