RT Book, Section A1 Baumann, Leslie SR Print(0) ID 1174544166 T1 Overview of Acne T2 Cosmeceuticals and Cosmetic Ingredients YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071793988 LK dermatology.mhmedical.com/content.aspx?aid=1174544166 RD 2024/03/29 AB Four main etiologic factors have been implicated in the pathophysiology of acne: sebaceous gland hyperactivity, inflammation, abundance of Propionibacterium acnes, and dysfunction of the desquamation of the hair follicle (see Chapter 64, Anti-inflammatory Agents). These causal elements work interdependently and are mediated by such important influences as diet, stress, heredity, and hormonal activity.