RT Book, Section A1 Weiss, Robert A. A1 Weiss, Margaret A. A1 Beasley, Karen L. SR Print(0) ID 1175620926 T1 Sclerosing Solutions T2 Sclerotherapy and Vein Treatment, 2e YR 2012 FD 2012 PB McGraw Hill LLC PP New York, NY SN 9780071485425 LK dermatology.mhmedical.com/content.aspx?aid=1175620926 RD 2024/04/23 AB Although it might appear deceptively simple, it is not always easy to sclerose a varicose vein. Even a small amount of damage will produce intravascular thrombus, but thrombosis alone usually does not obliterate the vessel. Intact endothelium contains tissue plasminogen activator that can dissolve thrombus. A thrombosed vessel with intact endothelium will simply recanalize.