RT Book, Section A1 Weiss, Robert A. A1 Weiss, Margaret A. A1 Beasley, Karen L. SR Print(0) ID 1175621272 T1 Foam Sclerotherapy T2 Sclerotherapy and Vein Treatment, 2e YR 2012 FD 2012 PB McGraw Hill LLC PP New York, NY SN 9780071485425 LK dermatology.mhmedical.com/content.aspx?aid=1175621272 RD 2024/10/03 AB Sclerotherapy with a foamed solution has become the standard treatment of many varicosities, perforating veins, reticular veins, and larger telangiectasias or venulectasias (1.0–2 mm). Although any detergent solution may be agitated with air and foamed, the two most popular solutions that are typically foamed are the detergent solutions, sodium tetradecyl sulfate (STS, sold in the United States as Sotradecol®; Bioniche Pharma, USA, LLC, Lake Forest, IL) and polidocanol (POL, sold in the United States as Asclera®; Chemische Fabrik Kreussler & Co., GmbH, Wiesbaden, Germany). Currently, to agitate and foam these U.S. Food and Drug administration (FDA)-cleared sclerosants is an off-label use in the United States. Foaming of solutions cannot be discussed or suggested by the companies manufacture or distribute the solutions in the United States because of the off-label use status.