RT Book, Section
A1 Pearson, David R.
A2 Soutor, Carol
A2 Hordinsky, Maria K.
SR Print(0)
ID 1190937691
T1 Skin Signs of Systemic Disease
T2 Clinical Dermatology: Diagnosis and Management of Common Disorders, 2e
YR 2022
FD 2022
PB McGraw-Hill Education
PP New York, NY
SN 9781264257379
LK dermatology.mhmedical.com/content.aspx?aid=1190937691
RD 2024/04/19
AB The  skin  is  immunologically  and  metabolically  dynamic,  highly  vascular,  and  directly  interfaces  with  the  environment.  It  also  plays  a  critical  role  in  maintenance  of  homeostasis,  protection,  and  sensation.  As  such,  cutaneous  pathology  is  a  window  to  many  systemic  disease  processes.  A  careful  history  and  thorough  physical  examination  of  the  skin,  hair,  nails,  and  mucosal  surfaces,  paying  particular  attention  to  morphology,  distribution,  and  other  subtle  clinical  clues,  may  result  in  critical  diagnostic,  prognostic,  and  therapeutic  benefit  that  is  acquired  at  the  bedside.  For  example,  recognition  of  nailfold  capillary  abnormalities  may  distinguish  the  hand  rash  seen  in  dermatomyositis  from  that  observed  in  eczema  and  lead  to  a  diagnosis  of  interstitial  lung  disease,  or  underlying  hepatitis  C  viral  infection  may  be  uncovered  through  identification  of  oral  erosive  lichen  planus.