RT Book, Section A1 Ahmed, Rehana A2 Soutor, Carol A2 Hordinsky, Maria K. SR Print(0) ID 1190939080 T1 Pruritus in Patients with No Underlying Skin Disease T2 Clinical Dermatology: Diagnosis and Management of Common Disorders, 2e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781264257379 LK dermatology.mhmedical.com/content.aspx?aid=1190939080 RD 2024/04/20 AB Pruritus (itch) is the unpleasant sensation of the skin that results in an urge to scratch. It is a major symptom of many cutaneous and systemic diseases. Pruritus can range from mild to severe and may be intermittent or chronic (lasting longer than 6 weeks). Pruritus can have a significant impact on health-related quality of life (HRQOL), and has been associated with depression, decreased sleep quality, and a negative impact on most quality of life categories.1 The authors of a case-control study of patients with chronic pruritus observed that the impact of chronic pruritus on HRQOL may be similar to that of chronic pain.2 Pruritus has multiple etiologies in patients with and without underlying skin disease. The International Forum for the Study of Itch recently published a clinical classification of pruritus 3 in which they proposed six categories for pruritus based on the underlying origin: