RT Book, Section A1 Weisberg, Edmund M. A1 Baumann, Leslie S. A2 Baumann, Leslie S. A2 Rieder, Evan A. A2 Sun, Mary D. SR Print(0) ID 1190671129 T1 Fragrance T2 Baumann’s Cosmetic Dermatology, 3e YR 2022 FD 2022 PB McGraw Hill LLC PP New York, NY SN 9780071794190 LK dermatology.mhmedical.com/content.aspx?aid=1190671129 RD 2024/10/04 AB SUMMARY POINTSWhat’s Important?Contact allergy to fragrance is a common problem often seen throughout the world, with fragrances consistently placed among the top 10 contact dermatitis allergens.Fragrance is the second most common allergen family associated with allergic contact dermatitis (after nickel), as well as the most often cited cause of such reactions to cosmetic products.What’s New?The use of the synthetic fragrance hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) was banned by the European Union in August 2019.The most common fragrance screeners in most baseline series include FM I, FM II, and balsam of Peru.Although banned in the EU, HICC may be deemed by some to be useful for screening, along with hydroperoxides of limonene and linalool, to diagnose fragrance allergy.What’s Coming?Continual retrospective studies will help to calibrate evolving patch test standards, helping to identify up-to-date allergens that are most appropriate to include in screening.