RT Book, Section A1 Tsoukas, Maria A1 Puyana, Carolina A2 Nouri, Keyvan SR Print(0) ID 1194728127 T1 Photodynamic Therapy T2 Skin Cancer: A Comprehensive Guide YR 2023 FD 2023 PB McGraw-Hill Education PP New York, NY SN 9781260453003 LK dermatology.mhmedical.com/content.aspx?aid=1194728127 RD 2024/04/19 AB SUMMARYPhotodynamic therapy (PDT) consists of interaction between a photosensitizer, light, and oxygen, resulting in the production of reactive oxygen species, which leads to targeted cell death.The two main topical photosensitizer prodrugs approved by the U.S. Food and Drug Administration (FDA) in the United States are 5-aminolevulinic acid (ALA) and its methylated derivative, methyl aminolevulinate (MAL).PDT is a safe and effective treatment methodology that is commonly used for actinic keratosis (AK), actinic cheilitis, and superficial nonmelanoma skin cancers.