RT Book, Section
A1 Baumann, Leslie S.
A2 Baumann, Leslie S.
A2 Rieder, Evan A.
A2 Sun, Mary D.
SR Print(0)
ID 1197533171
T1 Oily Skin
T2 Baumann’s Cosmetic Dermatology, 3e
YR 2022
FD 2022
PB McGraw Hill LLC
PP New York, NY
SN 9780071794190
LK dermatology.mhmedical.com/content.aspx?aid=1197533171
RD 2024/04/25
AB SUMMARY  POINTSWhat’s  Important?Oxidation  of  squalene  in  sebum  leads  to  comedones  and  milia.Oxidized  squalene  (squalene  peroxides)  has  deleterious  effects  on  skin  including  aging.The  Baumann  Skin  Type  Indicator  Questionnaire  can  accurately  predict  sebum  secretion  rates.The  average  sebum  production  rate  is  1  mg/10  cm2  every  3  hours.What’s  New?Oily  skin  is  divided  into  normal  oily  skin  and  very  oily  skin.Normal  oily  skin  has  normal  sebum  secretion  rates.Botulinum  toxin  Type  A  reduces  sebum  production.Various  cannabinoids  affect  sebum  production  differently.What’s  Coming?PPAR  and  retinoid  X  receptor  agonists  and  antagonists  may  be  developed  topically  to  control  sebum  production.The  effect  of  diabetes  medications  and  insulin-like  growth  factor-1  (IGF-1)  on  sebum  secretion  is  yet  to  be  established.Autophagy  regulates  sebum  production  and  is  suppressed  by  testosterone  as  well  as  IGF-1  and  increased  by  vitamin  D.  Development  of  products  that  increase  autophagy  in  sebocytes  may  lead  to  agents  to  decrease  skin  oiliness.More  data  are  needed  to  compare  differences  in  sebum  secretion  rates  among  different  ethnicities.