RT Book, Section
A1 Weisberg, Edmund M.
A1 Baumann, Leslie S.
A2 Baumann, Leslie S.
A2 Rieder, Evan A.
A2 Sun, Mary D.
SR Print(0)
ID 1197536280
T1 Fragrance
T2 Baumann’s Cosmetic Dermatology, 3e
YR 2022
FD 2022
PB McGraw Hill LLC
PP New York, NY
SN 9780071794190
LK dermatology.mhmedical.com/content.aspx?aid=1197536280
RD 2024/04/20
AB SUMMARY  POINTSWhat’s  Important?Contact  allergy  to  fragrance  is  a  common  problem  often  seen  throughout  the  world,  with  fragrances  consistently  placed  among  the  top  10  contact  dermatitis  allergens.Fragrance  is  the  second  most  common  allergen  family  associated  with  allergic  contact  dermatitis  (after  nickel),  as  well  as  the  most  often  cited  cause  of  such  reactions  to  cosmetic  products.What’s  New?The  use  of  the  synthetic  fragrance  hydroxyisohexyl  3-cyclohexene  carboxaldehyde  (HICC)  was  banned  by  the  European  Union  in  August  2019.The  most  common  fragrance  screeners  in  most  baseline  series  include  FM  I,  FM  II,  and  balsam  of  Peru.Although  banned  in  the  EU,  HICC  may  be  deemed  by  some  to  be  useful  for  screening,  along  with  hydroperoxides  of  limonene  and  linalool,  to  diagnose  fragrance  allergy.What’s  Coming?Continual  retrospective  studies  will  help  to  calibrate  evolving  patch  test  standards,  helping  to  identify  up-to-date  allergens  that  are  most  appropriate  to  include  in  screening.